ARC


Introduction

IVF stands for in vitro fertilization, in other words “fertilization in the glass”.  Another common moniker is “test tube baby”.  To perform IVF female eggs are fertilized with the male partners sperm in the laboratory.  The resulting embryos from this process are transferred into the female partner’s uterus (womb).  Typically the created embryo(s) are grown and cultured in the lab for 3-5 days.

One of the great advantages of IVF is that it can treat many causes of infertility.  These conditions include, tubal blockage, problems with ovulation, problems with the way the sperm and egg interact, poor sperm quality or quantity, older patients, problems with the cervix and many more.

Another great advantage of IVF is that it can be used to make specific diagnoses.  Since the embryo is created in the lab it gives physicians the ability to test the embryos for any genetic or chromosomal problems.  IVF therefore can be used to diagnose inheritable diseases.  Some of the most common diseases tested are cystic fibrosis, sickle cell disease, and chromosomal problems such as Downs’s syndrome and Turner’s syndrome.  Click For More On PGD and CGH

Finally IVF has the highest success rate in achieving a pregnancy for couples.  It also affords couples the option to store and freeze extra embryos that are created for future fertility.

Call today to make an appointment for IVF: 949-309-3330

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Egg Production: (ovarian hyperstimulation)

One of the goals during IVF is to allow the ovaries to produce multiple eggs.  To stimulate the ovary to do this, the patient is given hormonal medication (FSH analogues).  FSH (follicle stimulating hormone) is the hormone that is naturally responsible for stimulating the ovary.  The patient is given a daily or twice daily dose of FSH.  This allows the ovary to produce more than the usual 1 egg.  The patient is then monitored regularly to evaluate how she is responding to the medication.  

Monitoring is done in two ways; first the patient is monitored with Ultrasound evaluations.  These ultrasounds allow the doctor to visualize how many eggs are being produced.  Eggs develop and mature in cysts (also called follicles), by measuring these cysts (follicles) the physician can determine when the eggs are mature.  Second the patient is monitored by measuring estradiol levels (estrogen).  The estradiol levels also help the physician understand how well a patient is stimulating.

The typical patient is given FSH and stimulated for about 10-12 days.  Once it is determined that the eggs are mature the physician will simulate ovulation of the eggs by giving a medication called hCG (human chorionic gonadotropin).  The hormone mimics the hormone that naturally causes women to ovulate.  

Egg Production: (ovarian hyperstimulation)
Egg Production


An egg retrieval procedure is then scheduled.

 Call today to make an appointment for IVF: 949-309-3330

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Egg Retrieval

This procedure is performed usually 30-40 hours after hCG, or ovulation induction is administered.  The egg retrieval must be done prior to the patient ovulating on her own.  The eggs are retrieved using a needle that is guided by ultrasound.  The patient is given light anesthesia.

Call today to make an appointment for IVF: 949-309-3330

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Egg Fertilization

Once the eggs are retrieved they are identified under the microscope.  Each egg is typically surrounded by cells.  The embryologist will “strip” the cells away from the egg.  Sperm is also prepared for fertilization by “washing” the sperm. This process removes non-motile sperm and seminal fluid.  Once the preparation process is complete the sperm and egg are brought together.  There are two methods in which this can be performed.  The first method is an incubation method; where approximately 75,000 sperm are incubated with each egg in culture media.  18 hours later the embryologist evaluates the eggs to visualize if fertilization occurred.  The second method utilized is ICSI (intracytoplasmic sperm injection), Where a single sperm is selected and injected directly into the egg.

Egg Fertilization   Egg Fertilization      Egg Fertilization  IVF Microscope

    Egg after stripping                       ICSI                         Fertilization occured                IVF Microscope

                  

Call today to make an appointment for IVF: 949-309-3330

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Embryo Culture

Eggs that fertilized successfully are transferred into culture media to promote the growth of the now newly formed embryo.  Embryos are typically kept in this growth media for 48-72 hours at which time they should grow to be 6-8 cell embryos.  Embryos at this stage can be transferred back into the patients uterus (womb).  Alternately these embryos can be placed into a different culture media and grown to what is called the blastocyst stage (5 day old embryos).  Embryos can be transferred on day 5 as an alternative method.  Patients should discuss thoroughly the benefits and disadvantages of day 3 or day 5 transfers.

Embryo Culture     Embryo Culture       Embryo Culture      

       4 Cell Embryo                                            8 Cell Embryo                                           Blastocyst


Call today to make an appointment for IVF: 949-309-3330

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Embryo Transfer

The embryo transfer procedure is the procedure that places the embryo(s) in to the patient’s uterus (womb).  Embryo transfer is done by placing the best embryo(s) into a thin plastic catheter; this catheter is then passed through the vagina and cervix into the uterine cavity (womb).  Once in the appropriate location inside the uterus the embryos are injected inside.  Very often physicians will utilize an ultrasound to visualize the tip of the catheter and ensure its proper placement.

The embryos chosen for transfer are evaluated by the embryologist and physician to determine the best quality embryos.  The number of embryos transferred depends on the patient’s age, history, embryo quality, risk assessment, risk tolerance, and other diagnostic and clinical indicators.

Call today to make an appointment for IVF: 949-309-3330

Feel free to email us today one of our Irvine, CA Staff will help you get started: Click here...


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American Reproductive Center (ARC) is one of the most advanced fertility clinics in the United States. ARC offers national and international patients the most sophisticated fertility treatments available today. These services are available to patients in southern California as well as patients from other states and even other countries. We have extensive experience treating patients from around the world. Patients traveling from far away destinations come to us through recommendations or because they have failed their fertility treatments locally. This form of travel for fertility treatment is known as “medical tourism”. ARC is centrally located in southern California providing care to patients from Los Angeles, Los Angeles County, Orange County (OC) , Riverside County, and San Diego County. We have helped patients from other states as well. We also offer services that other states and nations don’t provide like egg donation, surrogacy, Pre-implantation genetic diagnosis (PGD), Sex selection / Gender Selection, Egg freezing and embryo freezing. Of course American Reproductive Centers also offers the usual treatment options including In Vitro Fertilization (IVF), Artificial Insemination (AI) and treating same-sex couples and single women. It is not uncommon for patients to forget website names, therefore many of our patients try using search engines by searching some of these specialized terms: fertility, fertility center, fertility clinic, infertility, and infertility center. These terms in combination with doctor, fertility doctor, infertility doctor will yield higher results. Since we also specialize in IVF, PGD, CGH, Sex Selection / Gender Selection, patients often search for IVF doctor, PGD specialist, Sex selection procedure, Gender Selection procedure. With all these terms and especially if the search includes Dr. Mazin Abdullah, Dr. Maher Abdallah, ARC, Dr. Abdullah, Dr. Abdallah, Dr. Mazin, Dr. Maher, and fertility doctor will yield more accurate results. If you live in a local city try using your local town to search e.g.: Laguna Niguel, irvine, Dana Point, Orange, Santa Ana, Tustin, Anaheim, Mission Viejo, Whittier, Garden Grove, Villa Park, San Juan Capistrano, San Clemente, Fountain Valley, Huntington, Huntington Beach, Long Beach, Corona, Torrance, Lake Forest, Whittier, Midway, Wesminster, Fullerton, Yorba Linda & Orange.
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